| 27th August | Hawick 20 – 20 Selkirk (Away) |
| 3rd September | Selkirk 22 – 15 Glasgow Hawks (Home) |
| 10th September | Jedforest (Home) Postponed to 18th November |
| 17th September | Musselburgh 8 – 29 Selkirk (Away) |
| 24th September | Selkirk 20 – 24 Edinburgh Academical (Home) |
| 1st October | Heriots 15 – 17 Selkirk (Away) |
| 8th October | Selkirk 28 – 14 GHA (Home) |
| 15th October | Marr 19 – 28 Selkirk (Away) |
| 22nd October | Selkirk 20 – 29 Currie Chieftains (Home) |
| 29th October | Selkirk 8 – 17 Hawick (Home) |
| 12th November | Glasgow Hawks 19 – 29 Selkirk (Away) |
| 18th November | Selkirk 36 – 10 Jedforest (Home) |
| 26th November | Jedforest 19 – 28 Selkirk (Away) |
| 3rd December | Selkirk 20 – 32 Musselburgh (Home) |
| 10th December | Edinburgh Academical (Away) – Postponed due to frozen pitch |
| 17th December | Heriots (Home) – Postponed due to frozen pitch |
| 7th January | GHA 17 – Selkirk 21 (Away) |
| 14th January | Selkirk 13 – 18 Marr (Home) |
| 21st January | Currie Chieftains (Away) – Postponed due to frozen pitch |
| 28th January | Edinburgh Academical 15 – 13 Selkirk (Away) |
| 18th February | Selkirk 5 – 22 Heriots (Home) |
| 25th February | Currie Chieftains 44 – 17 Selkirk (Away) |
| 20th March | Melrose 6 – 12 Selkirk – Border League Final (at Netherdale) |
| 25th March | Selkirk 38 – 7 Musselburgh (Home) – 2nd round Scottish Cup |
| 1st April | Ayr 49 – 13 Selkirk (Away) – Quarter Final Scottish Cup |
Kings of the Sevens
| Peebles 7s – 6th August 2022 | Bt Biggar (38-0), Bt Peebles (26-0), Semi-Final Lost Gala 29-24 (AET) |
| Hawick 7s – 13th August 2022 | Lost Edinburgh Accies (37-0), Lost Peebles (34-0) |
| Gala 7s – 20th August 2022 | Lost Peebles (22-0), Lost Edinburgh Accies (17-7) |
| Melrose 7s – 8th April 2023 | Lost GHA (29-0) |
| Berwick 7s – 16th April 2023 | Bt Gala (19-5) Bt Peebles (15-5) Semi-Final Lost Edinburgh Accies (24-0) |
| Langholm 7s – 22nd April 2023 | Bt Langholm (28-19) Bt Peebles (21-15) Semi-Final Lost Jed-forest (40-12) |
| Kelso 7s – 29th April 2023 | Bt Northumbria Uni (14-12) Lost Melrose (43-7) |
| Earlston 7s – 30th April 2023 | Bt Earlston (40-7) Quarter Final Lost Gala (19-17) |
| Jedforest 7s – 13th May | Bt Berwick (19-15) Quarter Final Lost Jed-Forest (38-0) |
| Selkirk 7s – 20th May | Bt Linlithgow (47-0) Quarter Final Lost Watsonians (19-33) |
